2023

Zhao X, Zhang Z, Zhu Q, Luo Y, Ye Q, Shi S, He X, Zhu J, Zhang D, Xia W, Zhang Y, Jiang L, Cui L, Ye Y, Xiang Y, Hu J, Zhang J, Lin C. Modeling human ectopic pregnancies with trophoblast and vascular organoids. Cell Reports, 42(6):112546. (2023)

He H*, Yang W*, Su N*, Zhang C, Dai J, Han F, Singhal M, Bai W, Zhu X, Zhu J, Liu Z, Tia W, Liu X, Zhang C, Jiang K, Huang W, Chen D, Wang Z, He X, Kirchhoff F, Li Z, Liu C, Huan J, Wang X, Wei W, Wang J, Augustin H, Hu J. Activating NO-sGC crosstalk in the mouse vascular niche promotes vascular integrity and mitigates acute lung injury. Journal of Experimental Medicine. 220(2):e20211422. (2023).  (*,  co-first authors).

2022

Zhang C, He H, Dai J, Li Y, He J, Yang W, Dai J, Han F, Kong W, Wang X, Zheng X, Pan W, Chen Z, Singhal M, Zhang Y, Guo F#, Hu J#. KANK4 promotes arteriogenesis by potentiating VEGFR2 signaling in a TALIN-1–dependent manner. Arteriosclerosis, Thrombosis, and Vascular Biology. 42:772-788. (2022).

Zhu S, Rao X, Qian Y, Chen J, Song R, Yan H, Yang X, Hu J, Wang X, Han Z, Liu R, Wong J, McCaughan G, Zheng X. Liver Endothelial Heg regulates vascular/biliary network patterning and metabolic donation via Wnt signaling. Cellular and Molecular Gastroenterology and Hepatology. 6:1757-1783. (2022).

2021

Singhal M, Gengenbacher M, Abdul Pari AA, Kamiyama M, Hai L, Kuhn BJ, Kallenberg, DM, Kulkarni SR, Camilli C, Preuss, S, Leuchs B, Mogler C, Espinet E, Besemfelder E, Heide D, Heikenwaler M, Sprick M, Trumpp A, Krijgsveld J, Schlesner M, Hu J, Moss S, Greenwood J, Augustin H. Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis, Science Translational Medicine, 13 (609), eabe6805. (2021).

Yang W*, He H*, Wang T, Su N, Zhang F, Jiang K, Zhu J, Zhang C, Niu K, Wang L, Yuan X, Liu N, Li L, Wei W, Hu J. Single-cell transcriptomic analysis reveals a hepatic stellate cell-activation roadmap and myofibroblast origin during liver fibrosis. Hepatology. 74: 2774–2790. (2021). (*,  co-first authors).

Shan H, Liu J, Shen J, Dai J, Xu G, Lu K, Han C, Wang Y, Xu X, Tong Y, Xiang H, Ai Z, Zhuang G, Hu J, Zhang Z, Li Y, Pan L, Tan L. Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2. Cell Chemical Biology. 28: 855–865. (2021). 

Gengenbacher N*, Singhal M*, Mogler C, Hai L, Milde L, Pari A, Besemfelder E, Fricke C, Baumann D, Gehrs S, Utikal J, Felcht M, Hu J, Schlesner M, Offringa M, Chintharlapalli S, Augustin H. Timed Ang2-targeted therapy identifies the Angiopoietin-Tie pathway as key regulator of fatal lymphogenous metastasis. Cancer Discovery. 11: 424–445. (2021). (*,  co-first authors).

2020

Dai J, Zhang C, Guo L, He H, Kai J, Huang Y, Zhang X, Zhang H, Wei W, Zhang Y, Lu L#, Hu J#. A necroptotic-independent function of MLKL in regulating endothelial cell adhesion molecule expression. Cell Death and Disease. 11: 282 (2020). (#,  co-corresponding authors).

Jiang H, Zhang L, Liu X, Sun W, Kato K, Chen C, Li X, Li T, Sun Z, Han W, Zhang H, Xiao Q, Yang Z, Hu J, Qin Z, Adams R, Gao X, He Y. Angiocrine FSTL1 (follistatin-like protein 1) insufficiency leads to atrial and venous wall fibrosis via SMAD3 activation. Arteriosclerosis, Thrombosis, and Vascular Biology. 40: 958–972. (2020).

2018

Singhal M*, Liu X*, Inverso D, Jiang K, Dai J, He H, Bartels S, Li W, Abdul Pari AA, Gengenbacher N, Besemfelder E, Hui L, Augustin H#, Hu J#. Endothelial cell fitness dictates the source of regenerating liver vasculature. Journal of Experimental Medicine. 215: 2497–2598. (2018). (*,  co-first authors; #,  co-corresponding authors).

Hu C*, Li W*, Tian F, Jiang K, Liu X, Cen J, He Q, Qiu Z, Keenest Y, Wang Z, Zhang H, Ji Y#, Hu J#, Hui L#. Arid1a regulates response to anti-angiogenic therapy in advanced hepatocellular carcinoma. Journal of Hepatology. 68: 465–475. (2018). (*,  co-first authors; #,  co-corresponding authors).

Guo L, Yang W, Huang Q, Qiang J, Hart JR, Wang W, Hu J, Zhu J, Liu N, and Zhang Y. Selenocysteine-specific mass spectrometry reveals tissue-distinct selenoproteomes and candidate selenoproteins. Cell Chemical Biology. 25: 1–9. (2018).

2017

Manavski Y, Abel T, Hu J, Kleinlützum D, Buchholz CJ, Belz C, Augustin H, Boon R, Dimmeler S. Endothelial transcription factor KLF2 negatively regulates liver regeneration via induction of activin A. Proceedings of the National Academy of Sciences. 114: 3993–3998. (2017).

Teichert M, Milde L, Holm A, Stanicek L, Gengenbacher N, Savant S, Ruckdeschel T, Hasanov Z, Srivastava K, Hu J, Hertel S, Bartol A, Schlereth K, Augustin H. Pericyte-expressed Tie2 controls angiogenesis and vessel maturation. Nature Communications. 8, 16106. (2017).

2016

SY, Lee JH, Kim SJ, Kim HC, Kim S, Kim SH, Kim C, Nakaoka Y, He Y, Augustin H, Hu J, Song PH, Kim YI, Kim P, Kim I, Koh GY. Amelioration of sepsis by TIE2 activation-induced vascular protection. Science Translational Medicine. 8, 335ra55. (2016).